Despite their lowly position Lancaster will pose a threat, with Ben Simm as one of their key bowlers as well as professional Timycen Maruma.
Barrow overcame Preston in a low scoring game last weekend where Jon Miles ended unbeaten on 72, with Daryl Wearing and new Professional Vaughn Van Jaarsveld taking 5 wickets each.
The league leaders also comfortably beat the Lancashire Colts in Sundays encounter at Ernest Pass.
In the other games Netherfield are back after their free weekend where they travel to Chorley on Saturday, before a cup clash at Leyland on Sunday.
Netherfield are hot on the heels of the leaders and will be keen to keep their winning momentum going. Their key games to come for John Mason's team with a local derby clash with Kendal as well as a big match against Blackpool to come.
Their is an interesting game at Vernon Road as St Anne's host Morecambe, Andy Kellet's men will be keen to build following their success at Lancaster last time out.
Morecambe have had a bit of an indifferent spell of late, but do have impressive victories over Netherfield and Kendal.
3rd placed Leyland host Darwen on Saturday, with David Makinsons men hot on the heels of the top two.
Second placed Fleetwood host Blackpool, whilst Kendal entertain Preston at Shap Road
On Sunday Blackpool host Kendal in The National Knockout whilst Leyland entertain Netherfield.
FIRST DIVISION FIXTURES
Barrow v Lancaster
Chorley v Netherfield
Fleetwood v Blackpool
Kendal v Preston
Leyland v Darwen
St Annes v Morecambe
Carnforth no game
Sunday 27th May
Carnforth v Lancashire Colts
SECOND DIVISION FIXTURES
Blackpool v Fleetwood
Darwen v Leyland
Lancaster v Barrow
Morecambe v St Annes
Netherfield v Chorley
Prteston v kendal
Carnforth no game